Parkinson’s Disease in New York
Recent research has shown that many of the symptoms of Parkinson’s disease can be effectively treated with medicinal cannabis.
Parkinson’s disease (PD) is a neurological and movement disorder with symptoms that progressively increase in both magnitude and severity. More than one million people in the United States are currently living with Parkinson’s disease. Although the cause of PD is not currently known and there is no known cure, a variety of treatments and therapy options are available, including surgery and medication that can help people suffering from PD better manage their symptoms. People living with Parkinson’s experience the malfunction and death of neurons, which are important nerve cells in the brain. Neurons in the portion of the brain known as the substantia nigra are most affected by PD. Many of these malfunctioning and dying neurons are responsible for producing a chemical called dopamine that sends important messages to the area of the brain that controls coordination and movement. As the disease progresses, a decreased amount of dopamine is produced, thereby resulting in an inability to control movement in a normal fashion.
Symptoms of Parkinson’s Disease
- Bradykinesia or slow movement
- Stiffness and rigidity
- A decline in balance and balance control
- Trouble smiling, frowning, or making other facial expressions
- A decline in handwriting skills (often handwriting becomes cramped and small)
- Slurred, slow, or whispery speech
- Difficulty chewing and swallowing foods, increased risk of choking, and increased salivation with possible drooling
- Constipation or loss of bowel and bladder control
- Emotional changes including increased fear, anxiety, isolation, and depression
- Sexual dysfunction, profuse sweating, and general aches and pains
- Sleep issues such as falling asleep suddenly during the day or frequently waking throughout the night
- Cognitive issues (dementia), diminished intellectual capacity, and hallucinations (typically in the later stages of PD)
Medical Marijuana as Part of a Parkinson’s Disease Treatment Plan
Citiva Medical will be expounding on existing research that points to calculated efficacy in the alleviation of Parkinson symptoms. Citiva Medical will begin work on developing treatments related to a 1985 study conducted by Snider and Consroe, indicating beneficial effects of CBD in Parkinson’s patients with Sinemet-induced dystonic dyskinesia.
CBD and THC have been shown from an observational perspective to alleviate “shakes” or tremors in Parkinson’s patients through the use of vapor inhalation. Citiva Medical has cannabis-based products designed to alleviate these symptoms and will have these products available upon opening our clinics in New York.
Research on Parkinson’s Disease and Cannabis Based Treatments
For more information on medicinal cannabis being used to treat Parkinson’s Disease, please click on the following links:
Survey on Cannabis Use in Parkinson’s Disease: Subjective Improvement of Motor Symptoms: Paper read at 2003 Symposium on the Cannabinoids, at Cornwall, ON, Canada.
Abstract: An anonymous questionnaire sent to all patients attending the Prague Movement Disorder Centre revealed that 25% of 339 respondents had taken cannabis, and 45.9% of these described some form of benefit.
Pertinent References: Venderova, K., E. Ruzicka, V. Vorisek, and P. Visnovsky. 2003.
Cannabis and Parkinson’s disease: Subjective improvement of symptoms and levodopa-induced dyskinesia.
Paper read at 2003 Symposium on the Cannabinoids, at Cornwall, ON, Canada.
Russo, E. Neuroprotection/Degenerative Diseases
Consroe, P. 1998. Brain cannabinoid systems as targets for the therapy of neurological disorders. Neurobiol Dis 5 (6 Pt B):534-51.
Frankel, J. P., A. Hughes, A. J. Lees, and G. M. Stern. 1990. Marijuana for parkinsonian tremor. J Neurol Neurosurg Psychiatry 53 (5):436.
Glass, M. 2001. The role of cannabinoids in neurodegenerative diseases. Prog Neuropsychopharmacol Biol Psychiatry 25 (4):743-65.
Sieradzan, K. A., S. H. Fox, M. Hill, J. P. Dick, A. R. Crossman, and J. M. Brotchie. 2001. Cannabinoids reduce levodopa-induced dyskinesia in Parkinson’s disease: a pilot study. Neurology 57 (11):2108-11.
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